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Oral bioavailability of intact TB-500 (a 43-amino-acid peptide) is expected to be very low based on established peptide pharmacokinetics

23 It is reported to affect males and females equally, and there is no racial predilection

doi:10.1038/s41591-023-02597-w 208

Plant Cell 19:18511865 Roxas VP, Smith RK, Allen ER, Allen RD (1997) Over-expressionof glutathione S -transferase/glutathione peroxidase enhances thegrowth of transgenic tobacco seedlings during stress