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Cosmelan is ideal for treating facial pigmentation, especially when melasma is worsened by laser treatment

Hispidulin has been indicated with diverse mechanistic insights in cell cycle arrest: in gastric cancer AGS cells, it sustains NAG-1 (NSAID-activated gene-1) expression through ERK activation, followed by the downregulation of cyclin D1/E, and eventually induces G1/S arrest with apoptosis (Yu et al., 2013

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The correlations confirm the expected outcome, i.e., the salt stress induces ROS that affect the seedling growth and metabolism, activating the defense mechanism represented by l-Pro, GR activity, and CAT