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PGI-C = Patient Global Impression scale of change

132.4 mM NaCl, 5.4 mM KCl, 5 mM Na2HPO4, 1 mM NaH2PO4, 1.2 mM MgSO4 and 1 mM CaCl2, commonly supplemented with various additions that are added immediately before use: 2 mg/ml BSA, 10 mM glucose, 0.5 or 1.0 mM DTT, 1 mM pyruvate (11 g per 100 ml), 10 mM HEPES, 0.01 mg/ml phenol red and buffered to pH 7.4 with NaOH

You want to ensure that every supplement you take is actually serving a purpose and, more importantly, that they are working together rather than competing for absorption

For a deeper breakdown of GLP-1 gut side effects, see: "GLP-1 Side Effects and Gut Health." The Hidden Problem: When Slowed Digestion Disrupts Microbial Balance Many GLP-1 users report bloating, constipation, and a general feeling of digestive sluggishness