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In the TSHR-immunized murine model of Graves disease, Treg depletion (particularly CD25) induced thyroid lymphocytic infiltrates with transient or permanent hypothyroidism (19.2)

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Adults do maintain brown fat deposits, primarily in the supraclavicular region (above the collarbones), along the spine, and around major blood vessels

GI side effects may temporarily worsen during the first four to eight weeks as the GIP receptor agonism effect is added

Structure insights into selective coupling of G protein subtypes by a class B G protein-coupled receptor