Gab 2 Polyclonal Antibody, 50ul[BT-AP03411] Pipette Micro Tips form a cytokine receptor gene

form a cytokine receptor gene cluster in a region mapped to chromosome 2q12

liver and brain but not in other tissues

tissue specificity:Detected in whole brain

The protein encoded by this gene resides in the golgi| and constitutes one of the 8 subunits of the conserved oligomeric Golgi (COG) complex| which is required for normal golgi morphology and localization

The protein encoded by this gene is closely related to STAM| an adaptor protein involved in the downstream signaling of cytokine receptors| both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM)

Gab 2 Polyclonal Antibody, 50ul[BT-AP03411] Pipette Micro Tips form a cytokine receptor geneGAB2 (GRB2 associated binding protein 2) is a member of the GRB2 associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T and B cell antigen receptors. The protein encoded by GAB2 is the principal activator of