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The tolerogenic profile of SEA-exposed DCs was confirmed by minimal upregulation of MHC, absence of CD80/CD86 upregulation and lack of Th1 and Th17-type cytokine production, such as IL-6, TNF and IL-12 (41), and maintain their ability to endocytose, which is lost during conventional maturation of DCs (42)

The reconstituted solution is stored at 2 to 8 degrees Celsius and used within 28 days