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Garetosmab, activin A inhibitor antibody for muscle-preservation combination regimens in obesity Recent Highlights: In June 2026, the company announced it would present new clinical data from the Phase 2 COURAGE trial that examines the effects of trevogrumab (anti-GDF8) on lean mass in people with obesity treated with semaglutide

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There were also post-marketing reports of acute pancreatitis in patients taking exenatide which were submitted to the Food and Drug Administration (FDA) and were published in the literature [70,71,72,73]