PCDB7 Rabbit Polyclonal Antibody, 20ul Low-speed Centrifuges The lack of RFX binding

The lack of RFX binding activity in complementation group C results from mutations in the RFX5 gene encoding the 75-kD subunit of RFX (Steimle et al

and a dysmorphic facial appearance

The gene was formerly referred to as CYP2A3

This gene product is a secreted neurotrophic factor but lacks a typical signal peptide

The encoded protein may be proteolytically processed as it contains a motif shown to be a protein scission motif in some members of this family (PMID: 11973329)

PCDB7 Rabbit Polyclonal Antibody, 20ul Low-speed Centrifuges The lack of RFX bindingThis gene is a member of the protocadherin beta gene cluster one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B cell and T cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular