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181 Similarly, sclareol significantly decreased levels of IL-1, TNF-, and IL-6 in Crohns disease models while upregulating tight junction proteins and preserving mucosal structure, indicating immunomodulatory and barrier-stabilizing roles

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Substantial tumor suppression was achieved both in vitro and in vivo using the photoresponsive antibodysiRNA combination (PARC), wherein photoirradiation facilitated the controlled release of siRNA, leading to a reduction in intracellular PD-L1 mRNA And an 86% decrease in protein levels