Phospho-Akt (S473) mouse Monoclonal Antibody(7F9), 100ul Gene Synthesis and an intracellular kinase domain

and an intracellular kinase domain

3 ubiquitin-protein ligase

and also forms a complex with EPS8 and SOS1 that mediates signal transduction from Ras to Rac

and E3) of the large pyruvate dehydrogenase complex

Activity of this protein regulates serine- and arginine-rich (SR) proteins of the spliceosomal complex

Phospho-Akt (S473) mouse Monoclonal Antibody(7F9), 100ul Gene Synthesis and an intracellular kinase domainThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a