ERCC1 Polyclonal Antibody, 100ul Multi-Layer Cell Culture System and was first identified as

and was first identified as being upregulated in psoriasis tissue

This gene encodes a transmembrane protein that contains multiple epidermal growth factor repeats that functions as a regulator of cell growth

Multiple alternatively spliced transcript variants that encode different protein isoforms have been observed in this gene

cysteine S-conjugates S-dichlorovinylcysteine (DCVC)

some of which use non-AUG (CUG) translation initiation codon

ERCC1 Polyclonal Antibody, 100ul Multi-Layer Cell Culture System and was first identified asThe product of ERCC1 functions in the nucleotide excision repair pathway, and is required for the repair of DNA lesions such as those induced by UV light or formed by electrophilic compounds including cisplatin. The encoded protein forms a heterodimer with the XPF endonuclease (also known as ERCC4), and the heterodimeric endonuclease catalyzes the 5' incision in the process of excising the DNA lesion. The heterodimeric endonuclease is also involved in