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FAK Polyclonal Antibody, 100ul[BT-AP09061] Cell Culture OAZ1 encodes antizyme 1

SKU: 20542281693

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FAK Polyclonal Antibody, 100ul[BT-AP09061] Cell Culture OAZ1 encodes antizyme 1This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal

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Description

OAZ1 encodes antizyme 1

This gene encodes the first and rate-limiting enzyme of the hexosamine pathway and controls the flux of glucose into the hexosamine pathway

Members of this family play important roles in apoptosis

Multiple transcript variants encoding several different isoforms have been found for this gene

and takes part in a negative feedback loop to attenuate cytokine signaling

FAK Polyclonal Antibody, 100ul[BT-AP09061] Cell Culture OAZ1 encodes antizyme 1This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal

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