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The cell cycle arrest during the G(0)/G(1) phase induced by fucoxanthin was related to a significant decrease in the protein expressions of phosphorylated-Rb (retinoblastoma protein), cyclin D (1 and 2), and cyclin-dependent kinase (CDK4) and significant upregulation of the protein levels of p15 INK4B and p27 Kip1 [30]

Brain Res 217:339349 Singhal SS, Yadav S, Roth C, Singhal J (2009) RLIP76: A novel glutathione-conjugate and multi-drug transporter

As indicated by the below graphs, the majority of participants unknowingly had suboptimal levels, but are still considered healthy by conventional standards

Nattokinase was shown to be capable of blocking thromboxane formation resulting in an inhibition of platelet aggregation without producing the side effect of bleeding [69]