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Trajenta (Linagliptin/Metformin) Trajenta 2023 sales: $1.815 billion Company/Developer: Boehringer Ingelheim Date of first FDA approval: May 2, 2011 Indications Trajenta is FDA-approved for: Trajenta is a DPP-4 inhibitor used as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus

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Boxed warning for Wegovy : Wegovy carries an FDA-boxed warning for a potential risk of thyroid C-cell tumors