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However, active GLP-1 is rapidly degraded by dipeptidyl peptidase IV, resulting in a remarkably short plasma half-life of approximately 2 min, with only 1015% of the active hormone remaining in circulation [47]

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View Source FEBS LETT GHK-Cu Stimulates Collagen Synthesis in Fibroblasts 1988 Maquart FX, Pickart L, Laurent M, Gillery P, Monboisse JC, Borel JP

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Palatin stopped development of the intranasal formulation in 2008

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