PEA-15 Polyclonal Antibody, 50ul[BT-AP07045] Lysosome resides in the critical region

resides in the critical region for VCFS/DGS on 22q11

They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation| nuclear and mitochondrial splicing| and ribosome and spliceosome assembly

and is considered to be an oncogene

Our adenoviral packaging system can accommodate large gene fragments and ensures high-level expression of target genes

with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane

PEA-15 Polyclonal Antibody, 50ul[BT-AP07045] Lysosome resides in the critical regionPEA15 (phosphoprotein enriched in astrocytes 15) encodes a death effector domain containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants.