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Btk Monoclonal Antibody, 100ul Immune Cell Analysis This phosphoprotein localizes to nuclear

SKU: 11226674614

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Btk Monoclonal Antibody, 100ul Immune Cell Analysis This phosphoprotein localizes to nuclearThe protein encoded by this gene plays a crucial role in B cell development. Mutations in this gene cause X linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.

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Description

This phosphoprotein localizes to nuclear bodies where it functions as a transcription factor and tumor suppressor

The nuclear form is localized in a granular pattern in the heterochromatin region beneath the nuclear envelope

MDK encodes a member of a small family of secreted growth factors that binds heparin and responds to retinoic acid

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|enzyme regulation:Three specific sites

Btk Monoclonal Antibody, 100ul Immune Cell Analysis This phosphoprotein localizes to nuclearThe protein encoded by this gene plays a crucial role in B cell development. Mutations in this gene cause X linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.

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