EGFR(Phospho Tyr869) Polyclonal Antibody, 20ul Digital Burette DUSP14 contains the consensus DUSP

DUSP14 contains the consensus DUSP C-terminal catalytic domain but lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al

A pseudogene of this gene is found on chromosome 11

which appears to have increased activity

adipocyte differentiation

The mitochondrially-encoded subunits function in electron transfer| and the nuclear-encoded subunits may function in the regulation and assembly of the complex

EGFR(Phospho Tyr869) Polyclonal Antibody, 20ul Digital Burette DUSP14 contains the consensus DUSPThe protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.