Presenilin 1 Polyclonal Antibody, 20ul Monoclonal Antibodies Diseases associated with OXR1 include
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Presenilin 1 Polyclonal Antibody, 20ul Monoclonal Antibodies Diseases associated with OXR1 includeAlzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1; PSEN2) or in the amyloid precursor protein (APP). These disease linked mutations result in increased production of the longer form of amyloid beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma secretase, an enzyme that cleaves APP.
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