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Cells either received 200 M TBHP alone or co-incubation with NAC, NACET, or diNAC at a range of concentrations, where 200 M had been previously demonstrated to be the maximum concentration to not significantly affect cell viability in ARPE-19 cells [25]

Long-acting agents seem to have a lower incidence of gastrointestinal adverse effects (166), likely due to tachyphylaxis in gastric emptying with sustained GLP-1R stimulation