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Phospho-ATRIP (S68) Polyclonal Antibody, 50ul Reservoirs Patients with mutations in this

SKU: 60791959007

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SEK185.00 SEK224.00

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Phospho-ATRIP (S68) Polyclonal Antibody, 50ul Reservoirs Patients with mutations in thisATRIP (ATR interacting protein) encodes an essential component of the DNA damage checkpoint. The encoded protein binds to single stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for ATRIP.

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Description

Patients with mutations in this gene have altered levels of sphingolipid and phospholipids in the brain

arterioles and vas deferens

This gene encodes a member of the Y family of specialized DNA polymerases

This gene is expressed at significantly lower levels in non-small cell lung cancer cells

Transcriptional adapter 2-alpha encoded by TADA2A is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex

Phospho-ATRIP (S68) Polyclonal Antibody, 50ul Reservoirs Patients with mutations in thisATRIP (ATR interacting protein) encodes an essential component of the DNA damage checkpoint. The encoded protein binds to single stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for ATRIP.

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