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Penetration enhancers like niacinamide or low molecular weight hyaluronic acid are commonly added in better formulations to improve dermal delivery

The two peptides come from different structural classes and are studied for activity at different points in the repair cascade.nnBPC-157 is a synthetic 15-amino-acid peptide derived from a partial sequence of a protein found in human gastric juice.nnTB-500 is a synthetic peptide based on the Thymosin Beta-4 sequence, a 43-amino-acid polypeptide naturally expressed in many human tissues.nnThe combination is one of the most-cited multi-peptide reference systems in preclinical regenerative-research literature, used by researchers examining how angiogenic and cytoskeletal-remodelling pathways interact in soft-tissue and musculoskeletal models

Add it to the water phase and keep processing temperatures below 40 C (104F)

doi: 10.1016/j.ijbiomac.2023.128999 131