APX-115 free base - CAS# 1270084-92-8 60419 HS Tariff Code: 382200

HS Tariff Code: 382200

Mäkinen P

InChi: InChI=1S/C24H23FN4O3/c25-20-8-5-15(14-21-17-3-1-2-4-18(17)22(30)27-26-21)13-19(20)24(32)29-11-9-28(10-12-29)23(31)16-6-7-16/h1-5

the PIK3CA H1047R mutant breast cancer model KPL-4

Presenter: Les H

APX-115 free base - CAS# 1270084-92-8 60419 HS Tariff Code: 382200APX 115 free base, CAS No. 1270084 92 8, also known as EWHA 18278, is a potent, orally active pan NADPH oxidase (Nox) inhibitor. APX 115 protects development of diabetic nephropathy in podocyte specific NOX5 transgenic mice. APX 115 might be a promising therapeutic agent for the treatment of DN because of its pan NOX inhibitory activity, including its NOX5 inhibitory activity, and also owing to its anti inflammatory effect. Product information CAS