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Adapted from episode 140 of The Perfect Stool podcast and edited for readability with Lindsey Parsons, EdD

Retrieved 2014-07-27

The Phase I trial of the novel HDAC inhibitor Bisthianostat (BIS, oral tablets, starting dose of 100 mg, escalated to 200/400 mg, administered twice weekly) demonstrated good safety as a monotherapy, with no Grade 3/4 non-hematologic toxicities

66,168 In conclusion, the crosstalk between different protein homeostasis machineries is a complex yet highly coordinated process that ensures cellular survival under stress conditions