NR0B2 Polyclonal Antibody, 20ul Miscellaneous The protein encoded by this

The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3)

tissue specificity:Highest levels in cerebellum

This gene encodes a member of a homeobox transcription factor gene family similiar to the Drosophila distal-less gene

The Ku p70/p86 dimer acts as regulatory subunit of the DNA-dependent protein kinase complex DNA-PK by increasing the affinity of the catalytic subunit PRKDC to DNA by 100-fold

The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage

NR0B2 Polyclonal Antibody, 20ul Miscellaneous The protein encoded by thisThe protein encoded by this gene is an unusual orphan receptor that contains a putative ligand binding domain but lacks a conventional DNA binding domain. The gene product is a member of the nuclear hormone receptor family, a group of transcription factors regulated by small hydrophobic hormones, a subset of which do not have known ligands and are referred to as orphan nuclear receptors. The protein has been shown to interact with retinoid and thyroid