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TFIIA- Alpha Polyclonal Antibody, 100ul Long RNA Synthesis all isoforms have N-terminal PDZ

SKU: 85788485094

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TFIIA- Alpha Polyclonal Antibody, 100ul Long RNA Synthesis all isoforms have N-terminal PDZAccurate transcription initiation on TATA containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A; MIM 180660) and several general initiation factors (summarized by DeJong and Roeder, 1993 [PubMed 8224848]). One of these factors is TFIIA, which when purified from HeLa extracts consists of 35 , 19 , and 12 kD subunits.

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Description

all isoforms have N-terminal PDZ domains while only longer isoforms (

is also included in the cullin family as it shares substantial sequence homology with CUL-1

tissue specificity:Moderately expressed in adult heart and brain

Introducing the PS1

and increased activity of this enzyme in infants with hemangiomas causes severe hypothyroidism

TFIIA- Alpha Polyclonal Antibody, 100ul Long RNA Synthesis all isoforms have N-terminal PDZAccurate transcription initiation on TATA containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A; MIM 180660) and several general initiation factors (summarized by DeJong and Roeder, 1993 [PubMed 8224848]). One of these factors is TFIIA, which when purified from HeLa extracts consists of 35 , 19 , and 12 kD subunits.

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