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p53 Monoclonal Antibody(6C4), 50ul Cell Biology Allelic variants are associated with

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p53 Monoclonal Antibody(6C4), 50ul Cell Biology Allelic variants are associated withThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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Description

Allelic variants are associated with prostate and brain cancer susceptibility

The encoded protein contains multiple conserved functional domains

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This particular family member preferentially binds acidic fibroblast growth factor and

The protein encoded by this gene is a DNA-binding zinc finger transcription factor and is a member of the fushi tarazu factor-1 subfamily of orphan nuclear receptors

p53 Monoclonal Antibody(6C4), 50ul Cell Biology Allelic variants are associated withThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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