APLP-1 Polyclonal Antibody, 50ul Bio-Reaction Tube Mutations in this gene are

Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia

Although the encoded protein is a member of the peptidase S1 family of serine proteases

|subunit:Heterotetramer that consists of two anti-parallel arranged heterodimers| each one formed by a small and a large subunit

strong structure and light weight

The protein encoded by ROR2 is a receptor protein tyrosine kinase and type I transmembrane protein that belongs to the ROR subfamily of cell surface receptors

APLP-1 Polyclonal Antibody, 50ul Bio-Reaction Tube Mutations in this gene areAPLP1 encodes a member of the highly conserved amyloid precursor protein gene family. The amyloid like protein 1 is a membrane associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development.