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APS Polyclonal Antibody, 20ul Monoclonal Antibody Preparation DNA binding

SKU: 10172261794

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APS Polyclonal Antibody, 20ul Monoclonal Antibody Preparation DNA bindingThe SH2B adaptor protein 2 encoded by SH2B2 is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt's lymphoma cell lines, it is tyrosine phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc Grb2 pathway.

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Description

DNA binding

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APS Polyclonal Antibody, 20ul Monoclonal Antibody Preparation DNA bindingThe SH2B adaptor protein 2 encoded by SH2B2 is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt's lymphoma cell lines, it is tyrosine phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc Grb2 pathway.

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