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PTM:Ubiquitinated

Binds multiple DNA elements such as cAMP-response element (CRE) and TPA response element (TRE) either as homodimer or heterodimer

Although its endogenous substrate has not been determined

predominantly in the basket terminal ring area

PKP3 Polyclonal Antibody, 20ul Polyclonal Antibodies Get the full benefits ofThis gene encodes a member of the arm repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may act in cellular desmosome dependent adhesion and signaling pathways. Two transcript variants encoding different isoforms have been found for this gene.