DNMBP Polyclonal Antibody, 100ul Cell Separation and Collection Mutations in this gene result

Mutations in this gene result in autosomal recessive spastic paraplegia

Three transcript variants encoding two different isoforms have been found for POLR2E

The protein encoded by this gene is a bifunctional enzyme that catalyzes the oxidative conversion of delta(5)-ene-3-beta-hydroxy steroid| and the oxidative conversion of ketosteroids

These proteins are characterized by the presence of seven alpha-helical transmembrane domains

Cut through any DNA restriction site with ease and precision

DNMBP Polyclonal Antibody, 100ul Cell Separation and Collection Mutations in this gene resultThis gene encodes a protein belonging to the guanine nucleotide exchange factor family, and which regulates the configuration of cell junctions. It contains multiple binding sites for dynamin and thus links dynamin to actin regulatory proteins. Polymorphisms in this gene have been linked to Alzheimer's disease in some populations, though there are conflicting reports of such linkages in other populations. Alternative splicing results in multiple