PERK(Phospho Thr981) Polyclonal Antibody, 20ul Bottle-Top Dispenser An important paralog of this

An important paralog of this gene is BTF3

ASCL1 encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors

which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione

and participates in the MAP kinase-mediated signaling cascade

It is located within a homozygously deleted region of a metastatic prostate cancer

PERK(Phospho Thr981) Polyclonal Antibody, 20ul Bottle-Top Dispenser An important paralog of thisThe protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in