Rb(Phospho Ser608) Polyclonal Antibody, 20ul Liquid Storage Consumables |cofactor:Binds 1 Fe(3+) ion per

|cofactor:Binds 1 Fe(3+) ion per subunit

ensuring smooth filtration

In nonmuscle cells| the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions| where it is involved in binding actin to the membrane

The encoded protein (CTD small phosphatase 1) plays a role in neuronal gene silencing in non-neuronal cells

but their full length sequences have not been determined

Rb(Phospho Ser608) Polyclonal Antibody, 20ul Liquid Storage Consumables |cofactor:Binds 1 Fe(3+) ion perThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.