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AAT Polyclonal Antibody, 100ul[BT-AP00075] In vitro Transcription DNA pol δ and DNA

SKU: 10424734055

4.4
SEK123.75 SEK147.75

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AAT Polyclonal Antibody, 100ul[BT-AP00075] In vitro Transcription DNA pol δ and DNAAASS encodes a bifunctional enzyme (aminoadipate semialdehyde synthase) that catalyzes the first two steps in the mammalian lysine degradation pathway. The N terminal and the C terminal portions of this enzyme contain lysine ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha aminoadipic semialdehyde. Mutations in AASS are associated with familial hyperlysinemia.

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Description

DNA pol δ and DNA pol e are multisubunit enzymes

An important paralog of this gene is CTNND1

and thus may play a crucial role in cardiogenesis and differentiation of the smooth muscle cell lineage

implying different ligand specificity

The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner

AAT Polyclonal Antibody, 100ul[BT-AP00075] In vitro Transcription DNA pol δ and DNAAASS encodes a bifunctional enzyme (aminoadipate semialdehyde synthase) that catalyzes the first two steps in the mammalian lysine degradation pathway. The N terminal and the C terminal portions of this enzyme contain lysine ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha aminoadipic semialdehyde. Mutations in AASS are associated with familial hyperlysinemia.

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