RPB7 Polyclonal Antibody, 20ul Sampling Tubes Defects in this gene are

Defects in this gene are a cause of early-onset epileptic encephalopathy

as well as in various cancer cell lines

the gene is expressed in many tissues and exhibits a intracellular vesicular pattern in Panc-1 cells (pancreatic cancer cells)

A processed pseudogene of this gene has been found on chromosome 1

and in transport of secretory cargo from the endoplasmic reticulum

RPB7 Polyclonal Antibody, 20ul Sampling Tubes Defects in this gene areThis gene encodes the seventh largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The protein functions in transcription initiation, and is also thought to help stabilize transcribing polyermase molecules during elongation.