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The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol

an octamer composed of pairs of each of the four core histones (H2A

Several transcript variants encoding different isoforms have been found for this gene

HSL Polyclonal Antibody, 20ul[BT-AP04236] Multi-Layer Cell Culture System Increase your productivity and revolutionizeHormone sensitive lipase by LIPE has a long and a short form, generated by use of alternative translational start codons. The long form is expressed in steroidogenic tissues such as testis, where it converts cholesteryl esters to free cholesterol for steroid hormone production. The short form is expressed in adipose tissue, among others, where it hydrolyzes stored triglycerides to free fatty acids.