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CLN3 Polyclonal Antibody, 50ul Centrifugal Filter These receptors are heteromeric protein

SKU: 10913595726

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SEK185.00 SEK208.00

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CLN3 Polyclonal Antibody, 50ul Centrifugal Filter These receptors are heteromeric proteinThis gene encodes a protein that is involved in lysosomal function. Mutations in this, as well as other neuronal ceroid lipofuscinosis (CLN) genes, cause neurodegenerative diseases commonly known as Batten disease or collectively known as neuronal ceroid lipofuscinoses (NCLs). Many alternatively spliced transcript variants have been found for this gene.

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Description

These receptors are heteromeric protein complexes with multiple subunits

LMX1B encodes a member of LIM-homeodomain family of proteins containing two N-terminal zinc-binding LIM domains

This protein is also thought to modify lipid metabolism and insulin-regulated gene expression

Mutations in TMPO are associated with dilated cardiomyopathy

Some patients also develop Cockayne syndrome

CLN3 Polyclonal Antibody, 50ul Centrifugal Filter These receptors are heteromeric proteinThis gene encodes a protein that is involved in lysosomal function. Mutations in this, as well as other neuronal ceroid lipofuscinosis (CLN) genes, cause neurodegenerative diseases commonly known as Batten disease or collectively known as neuronal ceroid lipofuscinoses (NCLs). Many alternatively spliced transcript variants have been found for this gene.

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