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PTK2 encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents

This gene also participates in several oncogenic rearrangements resulting in anaplastic lymphoma and mixoid chondrosarcoma| and may play a role in the NF-kappaB pathway

The antigen is being used as a target for immunotherapy treatment of human carcinomas

Mutations in CYP27A1 cause cerebrotendinous xanthomatosis

PO3F3 Polyclonal Antibody, 50ul Mini dry bath Ready to take your experimentsThis gene encodes a POU domain containing protein that functions as a transcription factor. The encoded protein recognizes an octamer sequence in the DNA of target genes. This protein may play a role in development of the nervous system.