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AMACR Monoclonal Antibody, 100ul NGS Oligos Overexpression of this gene has

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AMACR Monoclonal Antibody, 100ul NGS Oligos Overexpression of this gene hasThis gene encodes a racemase. The encoded enzyme interconverts pristanoyl CoA and C27 bile acylCoAs between their (R) and (S) stereoisomers. The conversion to the (S) stereoisomers is necessary for degradation of these substrates by peroxisomal beta oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult onset sensorimotor neuropathy, pigmentary retinopathy, and

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Description

Overexpression of this gene has been implicated in tumorigenesis

have been reported

such as C/EBP and LAP (liver activator protein)

is an integral membrane protein found on the cytoplasmic side of the endoplasmic reticulum and the Golgi apparatus

This gene is located in the male-specific region of the Y chromosome

AMACR Monoclonal Antibody, 100ul NGS Oligos Overexpression of this gene hasThis gene encodes a racemase. The encoded enzyme interconverts pristanoyl CoA and C27 bile acylCoAs between their (R) and (S) stereoisomers. The conversion to the (S) stereoisomers is necessary for degradation of these substrates by peroxisomal beta oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult onset sensorimotor neuropathy, pigmentary retinopathy, and

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