Cbl Monoclonal Antibody, 50ul sgRNA customized design The encoded protein is thought

The encoded protein is thought to act as a regulator of breast cancer growth and progression by binding to a phosphorylated form of integrin beta4

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Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546

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Cbl Monoclonal Antibody, 50ul sgRNA customized design The encoded protein is thoughtThis gene is a proto oncogene that encodes a RING finger E3 ubiquitin ligase. The encoded protein is one of the enzymes required for targeting substrates for degradation by the proteasome. This protein mediates the transfer of ubiquitin from ubiquitin conjugating enzymes (E2) to specific substrates. This protein also contains an N terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine phosphorylated substrates and