Cortactin Monoclonal Antibody, 100ul RNA Synthesis YEATS4 has been shown to

YEATS4 has been shown to be amplified in tumors

Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS)

and ASPSCR1 (alveolar soft part sarcoma chromosome region

TRAF proteins are associated with

Rho GEFs regulate the activity of small Rho GTPases by stimulating the exchange of guanine diphosphate (GDP) for guanine triphosphate (GTP) and may play a role in neural morphogenesis

Cortactin Monoclonal Antibody, 100ul RNA Synthesis YEATS4 has been shown toThis gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase