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IP3R-I Polyclonal Antibody, 20ul[BT-AP04603] Gloves Deletion mutations in this gene

SKU: 11181612070

4.6
PLN97.20 PLN129.20

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IP3R-I Polyclonal Antibody, 20ul[BT-AP04603] Gloves Deletion mutations in this geneITPR1 (inositol 1,4,5 trisphosphate receptor type 1) encodes an intracellular receptor for inositol 1,4,5 trisphosphate. Upon stimulation by inositol 1,4,5 trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in ITPR1 cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for ITPR1.

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Description

Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome

is located approximately 25 kb away from CYP1A1 on chromosome 15

possibly a steroid

elicits a potent vasodilation and inhibition of platelet aggregation through binding to this receptor

With a powerful speed of 7000rpm and a capacity of 2ml/1

IP3R-I Polyclonal Antibody, 20ul[BT-AP04603] Gloves Deletion mutations in this geneITPR1 (inositol 1,4,5 trisphosphate receptor type 1) encodes an intracellular receptor for inositol 1,4,5 trisphosphate. Upon stimulation by inositol 1,4,5 trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in ITPR1 cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for ITPR1.

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