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NCYM Polyclonal Antibody, 50ul Cell Culture Plates PABPC5 encodes poly(A) binding protein

SKU: 11182374974

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NCYM Polyclonal Antibody, 50ul Cell Culture Plates PABPC5 encodes poly(A) binding proteinThis gene is transcribed in antisense to the v myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog gene (MYCN). It is thought to encode a small, novel protein that stabilizes MYCN, prevents apoptosis, and promotes cell proliferation. Transcripts at this locus may also act directly as functional RNAs to recruit transcriptional regulators to the promoter of MYCN and stimulate transcription of this oncogene. This gene therefore

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Description

PABPC5 encodes poly(A) binding protein cytoplasmic 5 that binds to the polyA tail found at the 3' end of most eukaryotic mRNAs

thereby disrupting the cascade and preventing damage to host cells

It prevents assembly and promotes disassembly of microtubules

Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2)

Electronic control provides fatigue-free operation

NCYM Polyclonal Antibody, 50ul Cell Culture Plates PABPC5 encodes poly(A) binding proteinThis gene is transcribed in antisense to the v myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog gene (MYCN). It is thought to encode a small, novel protein that stabilizes MYCN, prevents apoptosis, and promotes cell proliferation. Transcripts at this locus may also act directly as functional RNAs to recruit transcriptional regulators to the promoter of MYCN and stimulate transcription of this oncogene. This gene therefore

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