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TGIF2 Polyclonal Antibody, 100ul Cryopreservation and it has been proposed

SKU: 11306813460

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TGIF2 Polyclonal Antibody, 100ul Cryopreservation and it has been proposedThe protein encoded by this gene is a DNA binding homeobox protein and a transcriptional repressor, which appears to repress transcription by recruiting histone deacetylases to TGF beta responsive genes. This gene is amplified and over expressed in some ovarian cancers. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 1. Read through transcription also exists between this gene and the

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Description

and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway

The protein encoded by this gene contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus

The encoded protein forms a stoichiometric complex with the mTOR kinase| and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase

which has a greater tendency to allow potassium to flow into a cell rather than out of a cell

EPS8L2 encodes a member of the EPS8 gene family

TGIF2 Polyclonal Antibody, 100ul Cryopreservation and it has been proposedThe protein encoded by this gene is a DNA binding homeobox protein and a transcriptional repressor, which appears to repress transcription by recruiting histone deacetylases to TGF beta responsive genes. This gene is amplified and over expressed in some ovarian cancers. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 1. Read through transcription also exists between this gene and the

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