HSP27 Monoclonal Antibody, 100ul Culture Tubes Interleukin-10 receptor subunit alpha encoded

Interleukin-10 receptor subunit alpha encoded by IL10RA is a receptor for interleukin 10

resulting in a decrease in sAPP-alpha production and increased amyloidogenic P3 peptide production

A pseudogene of this gene is found on chromosome 5

The two proteins share 50% sequence identity in this repeat-containing region

The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions

HSP27 Monoclonal Antibody, 100ul Culture Tubes Interleukin-10 receptor subunit alpha encodedThe protein encoded by this gene is induced by environmental stress and developmental changes. The encoded protein is involved in stress resistance and actin organization and translocates from the cytoplasm to the nucleus upon stress induction. Defects in this gene are a cause of Charcot Marie Tooth disease type 2F (CMT2F) and distal hereditary motor neuropathy (dHMN).