Integrin alphaX Polyclonal Antibody, 20ul Cell Separation and Collection Knockout mouse studies show defects

Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures

PRPF31 encodes a component of the spliceosome complex and is one of several retinitis pigmentosa-causing genes

Two transcript variants that encode different isoforms have been found for this gene

translation

and a cytoplasmic tail that differs from those of the classical cadherins

Integrin alphaX Polyclonal Antibody, 20ul Cell Separation and Collection Knockout mouse studies show defectsThis gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte specific integrin referred to as inactivated C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated