LIMK-1(Phospho Thr508) Polyclonal Antibody, 50ul Dialysis This putative nuclear transcription factor

This putative nuclear transcription factor most likely functions in regulating the response to growth factors

An important paralog of this gene is CLPTM1L

a lysosomal degradation pathway

MIM 611054) for background on liprins

The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes

LIMK-1(Phospho Thr508) Polyclonal Antibody, 50ul Dialysis This putative nuclear transcription factorThere are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein protein interactions. LIM kinase 1 and LIM kinase 2 belong to a small subfamily with a unique combination of 2 N terminal LIM motifs and a C terminal protein kinase