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Plakophilin 2 Polyclonal Antibody, 20ul Cell Transfection Two transcript variants resulting from

SKU: 12031096805

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Plakophilin 2 Polyclonal Antibody, 20ul Cell Transfection Two transcript variants resulting fromPKP2 encodes a member of the arm repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. PKP2 product may regulate the signaling activity of beta catenin. Two alternately spliced transcripts encoding two protein isoforms have been identified. A processed pseudogene with high

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Description

Two transcript variants resulting from alternative splicing have been identified

that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments

and may function as a neurotransmitter or a neuromodulator

These mutations have been shown to cause diverse changes in the pattern of DNA methylation

but it has modest inhibitory effects on IL-4 production from Th2 T cells

Plakophilin 2 Polyclonal Antibody, 20ul Cell Transfection Two transcript variants resulting fromPKP2 encodes a member of the arm repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. PKP2 product may regulate the signaling activity of beta catenin. Two alternately spliced transcripts encoding two protein isoforms have been identified. A processed pseudogene with high

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