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Akt Polyclonal Antibody, 100ul[BT-AP00336] Recombinant Protein Expression This kinase preferentially activates MAPK8/JNK

SKU: 12041936749

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Akt Polyclonal Antibody, 100ul[BT-AP00336] Recombinant Protein Expression This kinase preferentially activates MAPK8/JNKThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a

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Description

This kinase preferentially activates MAPK8/JNK kinase| and functions as a positive regulator of JNK signaling pathway

which contains a region that is highly similar to the N-terminal segment of BCL7A or BCL7C proteins

which mediates cell lysis

Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases

and it is part of a duplicated region of chromosome 1p36

Akt Polyclonal Antibody, 100ul[BT-AP00336] Recombinant Protein Expression This kinase preferentially activates MAPK8/JNKThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a

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