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EMR3 Polyclonal Antibody, 100ul Hybridoma Antibody Sequencing Mutations in this gene are

SKU: 12318466665

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EMR3 Polyclonal Antibody, 100ul Hybridoma Antibody Sequencing Mutations in this gene areADGRE3 (adhesion G protein coupled receptor E3) encodes a member of the class B seven span transmembrane (TM7) receptor family expressed predominantly by cells of the immune system. Family members are characterized by an extended extracellular region with a variable number of N terminal epidermal growth factor (EGF) like domains coupled to a TM7 domain via a mucin like spacer domain. ADGRE3 is closely linked to the gene encoding egf like molecule

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Description

Mutations in this gene are associated with Wolfram syndrome

an autosomic dominant congenital malformation

Small and compact to fit in the cabinet

PTM:Ubiquitinated when tyrosine phosphorylated and in a complex with GRB2

This protein shares limited sequence similarity with E1A and binds both the general transcription factor TBP and the tumor suppressor pRb in vitro

EMR3 Polyclonal Antibody, 100ul Hybridoma Antibody Sequencing Mutations in this gene areADGRE3 (adhesion G protein coupled receptor E3) encodes a member of the class B seven span transmembrane (TM7) receptor family expressed predominantly by cells of the immune system. Family members are characterized by an extended extracellular region with a variable number of N terminal epidermal growth factor (EGF) like domains coupled to a TM7 domain via a mucin like spacer domain. ADGRE3 is closely linked to the gene encoding egf like molecule

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